Bank of America
June 8, 2026
US Biopharmaceuticals: Is It Time To Reassess Biopharma
Sector ReportEquitiesHealth Care
The US Biopharma sector shows signs of fundamental improvement and easing regulatory headwinds, supported by attractive valuations relative to the S&P 500. Investors are increasingly reconsidering the sector as long-only exposure normalizes and hedge fund positioning begins to recover.
Key Takeaways
- 1.Biopharma sector fundamentals are showing signs of improvement despite ongoing concerns regarding rates and structural health care headwinds.
- 2.Policy and regulatory risks for Biopharma are easing, with FDA approvals on track and valuation remaining attractive relative to the S&P 500.
- 3.Market positioning is turning constructive, with long-only exposure normalizing and hedge funds beginning to exit three-year low positions.
Table of Contents
- Industry Overview
- Fundamentals improving... but are we there yet?
- Policy/ regulatory risks easing with Biopharma also cheap
- Positioning turning but there's much to go to catch up
- Disclosures
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Authors
Jason ZemanskyJacqueline PlessetSavita Subramanian
Securities
S&P 500
Themes
Biopharma RecoverySector Valuation DiscountInstitutional Positioning
Regions
North AmericaUnited States
