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Goldman Sachs

June 8, 2026

The Obesity Evolution: Refining Our Global Anti-Obesity Medication Market Model

Market ReportEquitiesHealth Care

Goldman Sachs has updated its 2030 Global Anti-Obesity Medication (AOM) market forecast to $114bn, driven by higher-than-expected adoption of oral medications and stronger international (OUS) sales growth. The firm anticipates a more balanced market share shift toward oral treatments, which are expected to command a larger portion of the total market.

Key Takeaways

  • 1.Raised 2030 Global Anti-Obesity Medication (AOM) TAM forecast to $114bn from $101bn.
  • 2.Shift in market dynamics toward oral medications, now expected to reach 40% of the 2030 global revenue TAM.
  • 3.Increased expectation for OUS (outside US) market penetration, forecasting 2030 total OUS obesity sales of $48bn vs. $39bn previously.

Table of Contents

  • GS Obesity Market Model Update: What’s Changed?
  • GS Obesity Model Update: Duopoly Dominates
  • GS Obesity Model Update: Mix Shift Toward Orals
  • Oral Obesity Pill Momentum: Expanding the AOM Market
  • Oral Obesity Pill Momentum: Monitoring the Launches
  • Oral Obesity Pill Momentum: NBRx a Key Leading Indicator
  • Oral Obesity Pill Momentum: Balancing Share Split Within Orals
  • US Obesity Market: Medicare Channel Unlock Ahead
  • GS Obesity Model Update: Increasing OUS Penetration
  • OUS Obesity Market Momentum: Underappreciated Runway
  • OUS Obesity Market Trends: Brazil
  • OUS Obesity Market Trends: India
  • OUS Obesity Market Trends: China
  • GS Obesity Model Update: Reflecting Lower Pricing Assumptions
  • Appendices

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Authors

James QuigleyAsad Haider, CFAJeff SuTheodora Rowe Beadle

Securities

WegovyFoundayo

Themes

Anti-Obesity Medication (AOM) Market GrowthOral Medication AdoptionInternational (OUS) Expansion

Regions

GlobalUnited StatesBrazilIndia