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Goldman Sachs

June 16, 2026

Healthcare Biotechnology Takeaways From Endo

Sector ReportEquitiesHealth Care

The report highlights key clinical data from the Endocrine Society Annual Meeting for biotech companies including NBIX, RYTM, AMLX, and TYRA. Data generally reinforced long-term efficacy and pipeline development progress across various indications.

Key Takeaways

  • 1.NBIX 2-year data for Crenessity in CAH showed sustained benefits including glucocorticoid reduction and cardiometabolic improvements.
  • 2.RYTM presented positive data for setmelanotide and bivamelagon in hypothalamic obesity with sustained BMI reductions.
  • 3.AMLX highlighted the economic burden of post-bariatric hypoglycemia (PBH) as exceeding $3.6B annually.

Table of Contents

  • Healthcare: Biotechnology: Takeaways from ENDO
  • Key takeaways
  • NBIX (CAH, PWS)
  • RYTM (HO/BBS/PWS)
  • AMLX (PBH)
  • TYRA (ACH)
  • Valuation and risks
  • GS Factor Profile
  • M&A Rank
  • Quantum
  • Disclosures

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