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Report published September 23, 2026

Goldman Sachs: US Morning Update – September 23, 2026

Goldman Sachs · September 23, 2026

The Goldman Sachs US Morning Update recaps overnight market moves, highlighting US 10-year yields near 4.96% and Brent crude near $100/bbl. Key research focuses on positive clinical trial data from Vertex and Amgen, along with analyst updates on AutoZone, O'Reilly, Valero, and Royal Caribbean.

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Finvaulta summarizes Goldman Sachs's analysis. Attribute opinions, forecasts, time-sensitive values, and chronology to the issuer and report date; do not treat this page as an independent verification or a current market-data source.

Key Takeaways

  • 1.Global equities showed mixed performance overnight as US 10-year Treasury yields sat 4 bps below 5.0% and Brent crude hovered just under $100/bbl.
  • 2.Biotech coverage highlighted positive clinical milestones: Vertex's Phase 2 inaxaplin data in APOL1-mediated kidney disease reduced proteinuria by 43%-45%, while Amgen reported positive Phase 3 results for dazodalibep in Sjögren's disease.
  • 3.China's lower crude imports have stabilized the oil market over the past six months, but elevated prices could sustain reduced import demand.

Table of Contents

  • Looking Ahead
  • Performance of Global Indices (as of September 23, 2026)
  • Rating & Conviction List Changes (as of September 23, 2026)
  • Today's Events (September 23, 2026)
  • Notable Research not on the Morning Call
  • Upcoming Webinars
  • Recent Podcasts
  • Webinar Replays
  • Global Market Intelligence
  • Resource Corner

Report data

Rating & Conviction List Changes (as of September 23, 2026) — as of September 23, 2026.

MetricEstimateContext
US 10-year Treasury Yield4.96%Trading 4 bps shy of the 5.0% mark overnight.
Brent Crude Price100.0 $/bblFront month Brent oil is trading just under $100/bbl.
Inaxaplin Proteinuria Reduction43.0%Reduced proteinuria by about 43%-45% in patients with milder APOL1 kidney disease.
Nikkei 225 Daily Performance1.4%Performance of Nikkei 225 index.
Valero Energy 6-month Price Target457.0 $Raised 6m price target to $457 from $365.
Source: FactSet, Bloomberg; Goldman Sachs Global Investment Research. This is a dated model snapshot, not a live forecast.

Reports in this series

Market Intelligence is shown in chronological order through this edition, published on September 23, 2026.

Part of the Market Intelligence series — view all 7 editions

Looking for the latest edition? Market Intelligence US Morning Update(67) (Oct 9, 2026)

  1. Sep 4Market Intelligence US Morning Update(60)
  2. Sep 10Market Intelligence US Morning Update(61)

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