Report published September 23, 2026
Goldman Sachs: US Morning Update – September 23, 2026
Goldman Sachs · September 23, 2026
The Goldman Sachs US Morning Update recaps overnight market moves, highlighting US 10-year yields near 4.96% and Brent crude near $100/bbl. Key research focuses on positive clinical trial data from Vertex and Amgen, along with analyst updates on AutoZone, O'Reilly, Valero, and Royal Caribbean.
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Finvaulta summarizes Goldman Sachs's analysis. Attribute opinions, forecasts, time-sensitive values, and chronology to the issuer and report date; do not treat this page as an independent verification or a current market-data source.
Key Takeaways
- 1.Global equities showed mixed performance overnight as US 10-year Treasury yields sat 4 bps below 5.0% and Brent crude hovered just under $100/bbl.
- 2.Biotech coverage highlighted positive clinical milestones: Vertex's Phase 2 inaxaplin data in APOL1-mediated kidney disease reduced proteinuria by 43%-45%, while Amgen reported positive Phase 3 results for dazodalibep in Sjögren's disease.
- 3.China's lower crude imports have stabilized the oil market over the past six months, but elevated prices could sustain reduced import demand.
Table of Contents
- Looking Ahead
- Performance of Global Indices (as of September 23, 2026)
- Rating & Conviction List Changes (as of September 23, 2026)
- Today's Events (September 23, 2026)
- Notable Research not on the Morning Call
- Upcoming Webinars
- Recent Podcasts
- Webinar Replays
- Global Market Intelligence
- Resource Corner
Report data
Rating & Conviction List Changes (as of September 23, 2026) — as of September 23, 2026.
| Metric | Estimate | Context |
|---|---|---|
| US 10-year Treasury Yield | 4.96% | Trading 4 bps shy of the 5.0% mark overnight. |
| Brent Crude Price | 100.0 $/bbl | Front month Brent oil is trading just under $100/bbl. |
| Inaxaplin Proteinuria Reduction | 43.0% | Reduced proteinuria by about 43%-45% in patients with milder APOL1 kidney disease. |
| Nikkei 225 Daily Performance | 1.4% | Performance of Nikkei 225 index. |
| Valero Energy 6-month Price Target | 457.0 $ | Raised 6m price target to $457 from $365. |
Reports in this series
Market Intelligence is shown in chronological order through this edition, published on September 23, 2026.
Part of the Market Intelligence series — view all 7 editions
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